Synthesis, Structural and Biomedical Characterization of Hydroxyapatite/Borosilicate Bioactive Glass Nanocomposites

In this work, a borosilicate glass sample (5SiO2–45B2O3–20Na2O–25CaO–5Ag2O) was added to nano-sized carbonated hydroxyapatite (CHA) powders with different contents up 20 wt% improve the bioactivity, antibacterial effect, physical and mechanical properties of resulting nanocomposites. The CHA BG nanocomposite were mixed, milled high-energy ball mill, then pressed into pellets under hydraulic pressure, finally sintered in muffle at 650 ºC. Subsequently, samples subjected X-ray diffraction (XRD) technique, Fourier transform infrared (FTIR) spectroscopy scanning electron microscopy (SEM) examine their structure, chemical composition microstructure, respectively. Furthermore, nanocomposites also measured. Moreover, vitro bioactivity prepared tested after being soaked simulated body fluid (SBF) solution for 10 days surfaces examined XRD SEM. addition, behavior these against E. coli S. aureus by disc-diffusion method. results obtained indicated that highest content possessed best properties. Based on results, can be used various biomedical applications.